Prof. Dr. med. Mario Siebler

• Siebler M, Köller H, Schmalenbach C, Müller HW (1988) GABA activated chloride currents in cultured rat hippocampal and septal region neurons can be inhibited by curare and atropine. Neurosci Lett. 93(2-3): 220–224.
• Köller H, Siebler M, Schmalenbach C, Müller HW (1990) GABA and glutamate receptor development of cultured neurons from rat hippocampus, septal region and neocortex. Synapse 5: 59–64.
• Köller H, Siebler M, Schmalenbach C, Müller HW (1990) Electrophysiological properties of rat septal region neurons during development in culture. Brain Res. 509: 85–90.
• Siebler M, Daffertshofer M, Hennerici M, Freund HJ (1990) Cerebral blood flow velocity alterations during obstructive sleep apnea syndrome. Neurology 40(9): 1461–1462.
• Meckenstock G, Gattermann N, Schneider W, Siebler M (1991) Leukostase-Syndrom mit Hirninfarkt bei rasch progredienter lymphatischer Leukämie. Dtsch med Wochenschr. 116: 1388–1392.
• Siebler M, Köller H, Rose G, Müller HW (1992) An improved graphical method for pattern recognition from spike trains of spontaneously active neurons. Exp Brain Res. 90: 141–146.
• Siebler M, Sitzer M, Steinmetz H (1992) Detection of intracranial emboli in patients with symptomatic extracranial carotid artery disease. Stroke 23(11): 1652–1654.
• Köller H, Siebler M, Müller HW (1993) Paroxysmal long-lasting depolarizations in cultured hippocampal neurons are generated by activation of NMDA and non-NMDA receptors. Synapse 14(3): 214–220.
• Siebler M, Köller H, Stichel CC, Müller HW, Freund HJ (1993) Spontaneous activity and recurrent inhibition in cultured hippocampal networks. Synapse 14(3): 206–213.
• Köller H, Siebler M, Pekel M, Müller HW (1993) Depolarization of cultured astrocytes by leukotriene B4. Evidence for the induction of a K+ conductance inhibitor. Brain Res. 612(1–2): 28–34.
• Siebler M, Pekel M, Köller H, Müller HW (1993) Strychnine-sensitive glycine receptors in cultured primary neurons from rat neocortex. Brain Res Dev Brain Res. 73(2): 289–292.
• Siebler M, Stoll G, Groth J (1993) Cogan´s syndrome presenting as psychosis in a geriatric patient. Geriatrics 2: 227–230.
• Köller H, Siebler M (1993) Impaired neuronal function induced by the immune mediator leukotriene B4. Brain Res 628(1–2): 313–316.
• Siebler M, Nachtmann A (1993) Cerebral hemodynamics in obstructive sleep apnea. Chest 103(4) : 1118–1119.
• Siebler M, Sitzer M, Rose G, Bendfeldt D, Steinmetz H (1993) Silent cerebral embolism caused by neurologically symptomatic high-grade carotid stenosis: Event rates before and after carotid endarterectomy. Brain 116: 1005–1015.
• Sitzer M, Fürst G, Fischer H, Siebler M, Fehlings T, Kleinschmidt A, Kahn T, Steinmetz H (1993) Between-method correlation in quantifying internal carotid stenosis. Stroke 24(10): 1513–1518.
• Köller H, Buchholz J, Siebler M (1994) Bacterial endotoxins impair electrophysiological properties of cultured astrocytes but not of cultured neurons. J Neurol  Sci. 124(2):156–162.
• Sitzer M, Fürst G, Siebler M, Steinmetz H (1994) Usefulness of an intravenous contrast medium in the characterization of high-grade internal carotid stenosis with color Doppler-assisted duplex imaging. Stroke 25(2):385–389.
• Siebler M, Kleinschmidt A, Sitzer M, Steinmetz H, Freund HJ (1994) Cerebral microembolism in symptomatic and asymptomatic high-grade internal carotid artery stenosis. Neurology 44(4):615–618.
• Siebler M, Rose G, Sitzer M, Bender A, Steinmetz H (1994) Real-time identification of cerebral microemboli with US feature detection by a neural network. Radiology 192(3):739–742.
• Siebler M, Nachtmann A, Sitzer M, Steinmetz H (1994) Anticoagulation monitoring and cerebral microemboli detection. Lancet 344(8921): 555.
• Köller H, Daubener W, Pilz K, Siebler M (1994) Lipopolysaccharides and leukotriene B4 induce independently regulated electrophysiological and immunological responses in cultured astrocytes. J Neuroimmunol. 55(2): 179–185.
• Köller H, von Giesen HJ, Siebler M (1995) Impairment of electrophysiological function of  astrocytes by cerebrospinal fluid from a patient with Waldenström's macroglobulinemia. J Neuroimmunol. 61: 35–39.
• Sitzer M, Söhngen D, Siebler M, Specker C, Rademacher J, Janda I, Aulich A, Steinmetz H (1995) Cerebral microembolism in patients with Sneddon's syndrome. Arch Neurol. 52(3): 271–275.
• Rose G, Siebler M (1995) Cooperative effects in neuronal ensembles. Exp Brain Res. 106: 106–110.
• Nachtmann A, Siebler M, Rose G, Sitzer M, Steinmetz H (1995) Cheyne-Stokes respiration in ischemic stroke. Neurology 45(4): 820–821.
• Georgiadis D, Kaps M, Siebler M, Hill M, König M, Berg J, Kahl M, Zunker P, Diehl B, Ringelstein EB (1995) Variability of Doppler microembolic signal counts in patients with prosthetic cardiac valves. Stroke 26(3): 439–443.
• Siebler M, Nachtmann A, Sitzer M, Rose G, Kleinschmidt A, Rademacher J, Steinmetz H (1995) Cerebral microembolism and the risk of ischemia in asymptomatic high-grade internal carotid artery stenosis. Stroke 26(11): 2184–2186.
• Sitzer M, Müller W, Siebler M, Hort W, Kniemeyer HW, Jäncke L, Steinmetz H (1995) Plaque ulceration and lumen thrombus are the main sources of cerebral microemboli in high-grade internal carotid artery stenosis. Stroke 26(7): 1231–1233.
• Sitzer M, Siebler M, Steinmetz H (1995) Silent emboli and their relation to clinical symptoms in extracranial carotid artery disease. Cerebrovasc Dis. 5: 121–123.
• Sitzer M, Siebler M, Rose G, Steinmetz H (1995) Cerebral microembolism in atherosclerotic carotid artery disease - facts and perspectives. Funct Neurol. 10(6):251–258.
• Köller H, Thiem K, Siebler M (1996) Tumor necrosis factor-alpha increases intracellular Ca2+ and induces a depolarization in cultured astroglial cells. Brain 119: 2021–2027.
• Köller H, Buchholz J, Siebler M (1996) Cerebrospinal fluid from multiple sclerosis patients inactivates neuronal Na+ current. Brain 119: 457–463.
• Markus H, Bland JM, Rose G, Sitzer M, Siebler M (1996) How good is intercenter agreement in the identification of embolic signals in carotid artery disease? Stroke 27(7): 1249–1252.
• Sitzer M, Siebler M, Steinmetz H (1996) Non-invasive evaluation of internal carotid stenosis with colour doppler-assisted duplex imaging. Clin Radiol. 51: 24–27.
• Sitzer M, Müller W, Rademacher J, Siebler M, Hort W, Kniemeyer HW, Steinmetz H (1996) Color-flow Doppler-assisted duplex imaging fails to detect ulceration in high-grade internal carotid artery stenosis. J Vasc Surg. 23(3): 461–465.
• Siebler M, Sitzer M, Rose G, Steinmetz H (1996) Microembolism in Carotid Artery Disease. Echocardiography 13(5): 529–534.
• Sitzer M, Müller W, Rademacher J, Siebler M, Hort W, Kniemeyer HW, Steinmetz H (1996) Detection of ulceration in high-grade internal carotid stenosis by means of color Doppler-assisted duplex imaging. A pathoanatomical validation study. J.E.M.U 17: 171–174.
• Markus HS, Ackerstaff R, Babikian V, Bladin C, Droste D, Grosset D, Levi C, Russell D, Siebler M, Tegeler C (1997) Intercenter agreement in reading Doppler embolic signals. A multicenter international study. Stroke 28(7): 1307–1310.
• Köller H, Siebler M, Hartung HP (1997) Immunologically induced electrophysiological dysfunction: implications for inflammatory diseases of the CNS and PNS. Prog Neurobiol. 52: 1–26.
• Sitzer M, Rose G, Fürst G, Siebler M, Steinmetz H (1997) Characteristics and clinical value of an intravenous echo-enhancement agent in evaluation of high-grade internal carotid stenosis. J Neuroimaging. 7: 22–25.
• Söhngen D, Siebler M, Wienen S, Kobbe G, Hollmig K, Schneider P, Boogen C, Heyll A, Schneider W (1997) Effect of rhG-CSF on platelets using in vitro bleeding time and transcranial Doppler examination. Beitr Infusionsther Transfusionsmed. 34: 161–165.
• Specker C, Rademacher J, Söhngen D, Sitzer M, Janda I, Siebler M, Steinmetz H, Schneider M (1997) Cerebral microemboli in patients with antiphospholipid syndrome. Lupus 6(8): 638–644.
• Siebler M, Steinmetz H, Freund HJ (1998) Therapeutic entrainment of circadian rhythm disorder by melatonin in a non-blind patient. J Neurol. 245(6–7): 327–328.
• Sitzer M, Skutta M, Siebler M, Sitzer G, Siegrist J, Steinmetz H (1998) Modifiable stroke risk factors in volunteers willing to participate in a prevention program. Neuroepi-demiology 17(4): 179–187.
• Jander S, Sitzer M, Schumann R, Schröter M, Siebler M, Steinmetz H, Stoll G (1998) Inflammation in high-grade carotid stenosis: a possible role for macrophages and T cells in plaque destabilization. Stroke 29(8): 1625–1630.
• Köller H, Allert N, Oel D, Stoll G, Siebler M (1998) TNF alpha induces a protein kinase C-dependent reduction in astroglial K+ conductance. Neuroreport 9(7): 1375–1378.
• Allert N, Köller H, Siebler M (1998) Ammonia-induced depolarization of cultured rat cortical astrocytes. Brain Res 782(1-2): 261–270.
• Ringelstein EB, Droste DW, Babikian VL, Evans DH, Grosset DG, Kaps M, Markus HS, Russell D, Siebler M (1998) Consensus on microembolus detection by TCD. International Consensus Group on Microembolus Detection. Stroke 29(3): 725–729.
• Specker C, Perniok A, Brauckmann U, Siebler M, Schneider M (1998) Detection of cerebral microemboli in APS — introducing a novel investgation method and implications of analogies with carotid artery disease. Lupus 7 Suppl 2: 75–80.
• Söhngen D, Wienen S, Siebler M, Boogen C, Scheid C, Schulz A, Kobbe G, Diehl V, Heyll A (1998) Analysis of rhG-CSF-effects on platelets by in vitro bleeding test and transcranial Doppler ultrasound examination. Bone Marrow Transpl. 22(11): 1087–1090.
• Kemeny V, Droste DW, Hermes S, Nabavi DG, Schulte-Altedorneburg G, Siebler M, Ringelstein EB (1999) Automatic embolus detection by a neural network. Stroke 30(4): 807–810.
• Neumann-Haefelin T, Wittsack HJ, Wenserski F, Siebler M, Seitz RJ, Mödder U, Freund HJ (1999) Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke. Stroke 30(8): 1591–1597.
• Cullinane M, Reid G, Dittrich R, Kaposzta Z, Ackerstaff R, Babikian V, Droste DW, Grossett D, Siebler M, Valton L, Markus HS (2000) Evaluation of new online automated embolic signal detection algorithm, including comparison with panel of international experts. Stroke 31(6): 1335–1341.
• Neumann-Haefelin T, Wittsack HJ, Fink GR, Wenserski F,  Li TQ; Seitz RJ, Siebler M, Mödder U, Freund HJ (2000) Diffusion- and perfusion-weighted MRI: influence of severe carotid artery stenosis on the DWI/PWI mismatch in acute stroke. Stroke 31(6): 1311–1317.
• Köller H, Schroeter M, Jander S, Stoll G, Siebler M (2000) Time course of inwardly rectifying K(+) current reduction in glial cells surrounding ischemic brain lesions. Brain Res. 872(1-2): 194–198.
• Stoll G, Schroeter M, Siebler M, Jander S (2000) Immunological aspects in stroke: therapeutic implications? CNS Drugs 14: 213–228.
• Neumann-Haefelin T, Wittsack HJ, Wenserski F, Li TQ, Moseley ME, Siebler M, Freund HJ (2000) Diffusion- and perfusion-weighted MRI in a patient with a prolonged reversible ischaemic neurological deficit. Neuroradiology 42(6): 444–447.
• Stoll G, Jander S, Sitzer M, Müller W, Sandmann W, Siebler M (2000) Die instabile Carotisstenose- eine entzündliche Erkrankung? Nervenarzt 71(12): 955–962.
• Jander S, Sitzer M, Wendt A, Schroeter M, Buchkremer M, Siebler M, Müller W, Sandmann W, Stoll G (2001) Expression of tissue factor in high-grade carotid artery  stenosis: association with plaque destabilization. Stroke 32(4): 850–854.
• CAVATAS Investigators 2001 Endovascular versus surgical treatment in patients with carotid stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomised trial. Lancet 357(9270): 1729–1737.
• Junghans U,  Seitz RJ, Aulich A, Freund HJ, Siebler M (2001) Bleeding risk of tirofiban, a nonpeptide GPIIb/IIIa platelet receptor antagonist in progressive stroke: an open pilot study. Cerebrovasc Dis. 12(4): 308–312.
• Junghans U, Seitz RJ, Wittsack HJ,  Aulich A, Siebler M (2001) Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a non-peptide platelet glycoprotein IIb/IIIa inhibitor: report of four cases. Radiology 221(3): 795–801.
• Junghans U, Seitz R, Ritzl A, Wittsack HJ, Fink GR, Freund HJ, Siebler M (2002). Ischemic brain tissue salvaged from infarction by the GP IIb/IIIa platelet antagonist tirofiban. Neurology 58: 476–478.
• Wittsack HJ, Ritzl A, Fink GR, Wenserski F, Siebler M, Seitz RJ, Mödder U, Freund HJ (2002) MR imaging in acute stroke: Diffusion-weighted and perfusion imaging parameters for predicting infarct size. Radiology 222(2): 397–403.
• Ommer A, Dziewanowski M, Pillny M, Huber R, Siebler M, Sandmann W (2002) Long-term results after carotid reconstruction in patients with completed stroke caused by cerebrovascular occlusive disease. Dtsch Med Wochenschr. 127(8): 370–375.
• Fiehler J, Fiebach JB, Gass A, Hoehn M, Kucinski T, Neumann-Haefelin T, Schellinger PD, Siebler M, Villringer A, Röther J (2002) Diffusion-weighted imaging in acute stroke-a tool of uncertain value? Cerebrovasc Dis. 14(3-4): 187–196.
• Siebler M, Seitz RJ, Hartung HP (2002) Pro, Kontra, Re zur Mikroemboliedetektion. Nervenarzt 73: 125–132.
• Scherer A, Siebler M, Aulich, A (2002) Virtual arterial endoscopy as a diagnostic aid in a patient with basilar artery fenestration and thromboembolic pontine infarct. AJNR Am J Neuroradiol. 23(7): 1237–1239.
• Röther J, Schellinger PD, Gass A, Siebler M, Villringer A, Fiebach JB, Fiehler J, Jansen O, Kucinski T, Schoder V, Szabo K, Junge-Hülsing GJ, Hennerici M, Zeumer H, Sartor K, Weiller C, Hacke W; Kompetenznetzwerk Schlaganfall Study Group (2002) Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours. Stroke 33(10): 2438–45.
• Huber R, Müller BT, Seitz RJ, Siebler M, Mödder U, Sandmann W (2003) Carotid surgery in acute symptomatic patients. Eur J Vasc Endovasc Surg.  25(1): 60–67.
• Görtz P, Köller H, Schwahn B, Wendel U, Siebler M (2003) Disturbance of cultured rat neuronal network activity depends on concentration and ratio of leucine and alpha-ketoisocaproate: implication for acute encephalopathy of maple syrup urine disease. Pediatr Res. 53(2): 320–324.
• Junghans U, Siebler M (2003) Cerebral microembolism is blocked by tirofiban, a selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist. Circulation 107(21): 2717–2721.
• Seitz RJ, Hamzavi M, Junghans U, Ringleb PA, Schranz C, Siebler M (2003) Thrombo-lysis with recombinant tissue plasminogen activator and tirofiban in stroke: preliminary observations. Stroke 34(8): 1932–1935.
• Otto F, Görtz P, Fleischer W, Siebler M (2003) Cryopreserved rat cortical cells develop functional neuronal networks on microelectrode arrays. J Neurosci Methods. 128(1–2): 173–181.
• Neumann-Haefelin T, du Mesnil de Rochemont R, Fiebach JB, Gass A, Nolte C, Kucinski T, Rother J, Siebler M, Singer OC, Szabo K, Villringer A, Schellinger PD; Kompetenznetz Schlaganfall Study Group (2004) Effect of incomplete (spontaneous and postthrombolytic) recanalization after middle cerebral artery occlusion: a magnetic resonance imaging study. Stroke 35(1): 109–114.
• Görtz P, Hoinkes A, Fleischer W, Otto F, Schwahn B, Wendel U, Siebler M (2004) Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity. J  Neurol Sci. 218(1–2): 109–114.
• Straub S, Junghans U, Jovanovic V, Wittsack HJ, Seitz RJ,  Siebler M (2004) Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion. Stroke 35(3): 705–709.
• Seitz RJ, Meisel S, Moll M, Wittsack HJ, Junghans U, Siebler M (2004) The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions. Neurology 62(11): 2110–2112
• Görtz P, Fleischer W, Rosenbaum C, Otto F, Siebler M (2004) Neuronal network properties of  human teratocarcinoma cell line-derived neurons. Brain Res. 1018: 18–25.
• Fiebach JB, Schellinger PD, Gass A, Kucinski T, Siebler M, Villringer A, Olkers P, Hirsch JG, Heiland S, Wilde P, Jansen O, Rother J, Hacke W, Sartor K; Kompetenznetzwerk Schlaganfall B5 (2004) Stroke magnetic resonance imaging Is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. Stroke 35(2) : 502–506.
• Wegener S, Gottschalk B, Jovanovic V, Knab R, Fiebach JB, Schellinger PD, Kucinski T, Jungehulsing GJ, Brunecker P, Muller B, Banasik A, Amberger N, Wernecke KD, Siebler M, Rother J, Villringer A, Weih M; MRI in Acute Stroke Study Group of the German Competence Network Stroke (2004). Transient ischemic attacks before ischemic stroke: preconditioning the human brain? A multicenter magnetic resonance imaging study. Stroke 35(3): 616–621. 
• Ritzl A, Meisel S, Wittsack HJ, Fink GR, Siebler M, Modder U, Seitz RJ (2004) Development of brain infarct volume as assessed by magnetic resonance imaging (MRI): follow-up of diffusion-weighted MRI lesions. J Magn Reson Imaging. 20(2): 201–207.
• Markus HS, Droste DW, Kaps M, Larrue V, Lees KR, Siebler M, Ringelstein EB (2005) Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using Doppler embolic signal detection:  the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) Trial. Circulation 111(17): 2233–2240.
• Georgiadis D, Lanczik O, Schwab S, Engelter S, Sztajzel R, Arnold M, Siebler M, Schwarz S, Lyrer P, Baumgartner RW (2005)  IV thrombolysis in patients with acute stroke due to spontaneous carotid dissection. Neurology 64(9): 1612–1614.
• Otto F, Kieseier BC, Görtz P, Hartung HP, Siebler M (2005) The pentapeptide QYNAD does not inhibit neuronal network activity. Can J Neurol Sci 32(3): 344–348.
• Seitz RJ, Meisel S, Moll M, Wittsack HJ, Junghans U, Siebler M (2005) Partial rescue of the perfusion deficit area by thrombolysis. J Magn Reson Imaging. 22(2): 199–205.
• Müller BT, Huber R, Henrich B, Adams O, Berns G, Siebler M, Jander S, Müller W, Loncar R, Godehardt E, Sandmann W (2005) Chlamydia pneumoniae, herpes simplex virus and cytomegalovirus in symptomatic and asymptomatic high-grade internal carotid artery stenosis. Does infection influence plaque stability? Vasa 34(3): 163–169.
• Seitz RJ, Meisel S, Weller P, Junghans U, Wittsack HJ, Siebler M (2005) Initial Ischemic Event: Perfusion-weighted MR Imaging and Apparent Diffusion Coefficient for Stroke Evolution. Radiology 237(3): 1020–1028.
• Klusmann A, Fleischer W, Waldhaus A, Siebler M, Mayatepek E (2005) Influence of D- arabitol and ribitol on the neuronal network activity. J Inher Metab Dis. 2005, 28:1181–3.
• Seitz RJ, Meisel S, Moll M, Wittsack HJ, Junghans U, Siebler M (2006) Partial Rescue of the perfusion deficit area by thrombolysis. J Magn Reson Imaging 22:199–205.
• Dittrich R, Ritter MA, Kaps M, Siebler M, Lees K, Larrue V, Nabavi DG, Ringelstein EB, Markus HS, Droste DW. The Use of Embolic Signal Detection in Multicenter Trials to Evaluate Antiplatelet Efficacy. Signal Analysis and Quality Control Mechanisms in the CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) Trial.  Stroke 2006 37:1065–9.
• Alldinger I, Siebler M, Peiper M, Cupisti K, Rado Y, Kindgen-Milles D, Knoefel WT. Episodic respiratory failure due to focal epileptic activity. Eur J Med Res. 2006, 21:90–92.
• Dohmen C, Sitzer M, Kessler KR, Siebler M, Malevani M, Huff W (2006) Post-Stroke-Depression: Algorithmus für ein standardisiertes diagnostisches Vorgehen in der klinischen Routine. Fortschritte in Neurologie und Psychiatrie 74:257–262.
• Linke S, Görtz P, Retzlik J, Baader SL, Gieselmann J, Siebler M, Junghans U, Kappler J (2006) Aldolase C/ZebrinII is released to the extracellular space after stroke and inhibits the network activity of cortical neurons. Neurochem Res. 2006, 31:1297–303.
• Georgiadis D, Siebler M. Detection of microembolic signals with transcranial Doppler ultrasound. Front Neurol Neurosci. 2006;21:194–205.
• Weller P, Wittsack HJ, Siebler M, Hömberg V, Seitz RJ. (2006) Motor recovery as assessed with isometric finger movements and perfusion magnetic resonance imaging after acute ischemic stroke. Neurorehabil Neural Repair. 20:390–7.
• Audebert HJ, Haberl RL, Hacke W, Handschu R, Schenkel J, Scibor M, Schleyer AM, Siebler M, Vatankhah B, Wiborg A, Widder B. Telemedicine in acute stroke care. Dtsch  Med Wochenschr. 2007; 132:431–436.
• Neuhaus O, Saleh A, van Oosterhout A, Siebler M (2007) Cerebellar infarction after gamma knife radiosurgery of a vestibular schwannoma. Neurology. 2007, 68:590.
• Schöbel FC, Jax T, Peters A, Keis I, Siebler M, Heintzen MP (2008) Patent foramen ovale: What causes water to flow uphill? - More views. Int J Cardiol. 2008, 124:43–50.
• Illes S, Fleischer W., Siebler M, Hartung H-P, Dihné M (2007) Development and pharmacological modulation of embryonic stem cell-derived neuronal network activity. Exp. Neurol 207:171–176.
• Hohlfeld T, Weber AA, Junghans U, Schumacher M, Boucher M, Schrör K, Siebler M (2007) Variable platelet response to aspirin in patients with ischemic stroke.Cerebrovasc Dis. 2007;24(1):43–50.
• Turowski B, Hanggi D, Siebler M. (2007) Intracranial bilateral vertebral artery dissection during anticoagulation after cerebral venous and sinus thrombosis (CSVT). Acta Neurochir (Wien) 149(8):793–7.
• Saleh A, Schroeter M, Ringelstein A, Hartung HP, Siebler M, Mödder U, Jander S. (2007) Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke. Stroke 38(10):2733–7.
• Weis-Müller BT, Huber R, Spivak-Dats A, Turowski B, Seitz R, Siebler M, Sandmann W. (2007) Indication for emergent revascularisation of acute carotid occlusion. Chirurg. 78(11):1041–1048
• Sergeeva OA, Fleischer W, Chepkova AN, Warskulat U, Häussinger D, Siebler M, Haas HL (2007). GABA A-receptor modification in taurine transporter knockout mice causes striatal disinhibition. J Physiol. 585:539–48.
• Seitz RJ, Siebler M. (2008) Platelet GPIIb/IIIa Receptor Antagonists in Human Ischemic Brain Disease. Curr Vasc Pharmacol. 6:29–36.
• Siebler M, Junghans U, Fiebach JB. Imaging in cerebrovascular atherosclerotic disease. Herz. 2008;33:482–8. 
• van Zon K, Lord WP, Lagor C, Theiss S, Brosig T, Siebler M. Stroke navigator – a clinical decision support system for acute stroke. AMIA Annu Symp Proc. 2008 Nov 6:1227.
• Lee JI, Wittsack HJ, Christaras A, Miese FR, Siebler M. Normalization of brain tissue lactate after hyperbaric oxygen therapy in a progressive stroke patient. Cerebrovasc Dis. 2008;26:447–8.
• Eickhoff SB, Dafotakis M, Grefkes C, Stöcker T, Shah NJ, Schnitzler A, Zilles K, Siebler M fMRI reveals cognitive and emotional processing in a long-term comatose patient. Exp Neurol. 2008;214:240–6.
• Otto F, Illes S, Opatz J, Laryea M, Theiss S, Hartung HP, Schnitzler A, Siebler M, Dihné M Cerebrospinal fluid of brain trauma patients inhibits in vitro neuronal network function via NMDA receptors.  Ann Neurol. 2009; 66:546–55.
• ACES Investigators. The Asymptomatic Carotid Emboli Study: study design and baseline results. Int J Stroke. 2009;4:398–405. 
• Bonati LH, Ederle J, McCabe DJ, Dobson J, Featherstone RL, Gaines PA, Beard JD, Venables GS, Markus HS, Clifton A, Sandercock P, Brown MM; CAVATAS Investigators. Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial. Lancet Neurol. 2009;8:908–17.
• Ederle J, Bonati LH, Dobson J, Featherstone RL, Gaines PA, Beard JD, Venables GS, Markus HS, Clifton A, Sandercock P, Brown MM; CAVATAS Investigators. Endovascular treatment with angioplasty or stenting versus endarterectomy in patients with carotid artery stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial. Lancet Neurol. 2009;8:898–907.
• Illes S, Theiss S, Hartung HP, Siebler M, Dihné M. Niche-dependent development of functional neuronal networks from embryonic stem cell-derived neural populations. BMC Neurosci. 2009;6:10/93.
• Seitz RJ, Sondermann V, Wittsack HJ, Siebler M. Lesion patterns in successful and failed thrombolysis in middle cerebral artery stroke. Neuroradiology. 2009;51:865–71.
• Görtz P, Opatz J, Siebler M, Funke SA, Willbold D, Lange-Asschenfeldt C. Transient reduction of spontaneous neuronal network activity by sublethal amyloid beta (1-42) peptide concentrations. J Neural Transm. 2009;116:351–5.
• Groiss SJ, Siebler M, Schnitzler A. Full recovery of adult onset opsoclonus myoclonus syndrome after early immunotherapy: A case report. Mov Disord. 2011 Jun 28. doi: 10.1002/mds.23854.
• Gerwig M, Guberina H, Esser AC, Siebler M, Schoch B, Frings M, Kolb FP, Aurich V, Beck A, Forsting M, Timmann D. Evaluation of multiple-session delay eyeblink conditioning comparing patients with focal cerebellar lesions and cerebellar degeneration. Behav Brain Res. 2010;15-212(2):143–51
• Dengler R, Diener HC, Schwartz A, Grond M, Schumacher H, Machnig T, Eschenfelder CC, Leonard J, Weissenborn K, Kastrup A, Haberl R; EARLY Investigators. Early treatment with aspirin plus extended-release dipyridamole for transient ischaemic attack or ischaemic stroke within 24 h of symptom onset (EARLY trial): a randomised, open-label, blinded-endpoint trial. Lancet Neurol. 2010;9:159–66
• Seitz RJ, Oberstrass H, Ringelstein A, Wittsack HJ, Siebler M. Failed recovery from thrombolysis is predicted by the initial diffusion weighted imaging lesion.Cerebrovasc Dis. 2011;31:580–7
• Siebler M, Hennerici M, Schneider D, von Reutern GM, Seitz RJ, Röther J, Witte OW,  Hamann G, Junghans U, Villringer A, Fiebach J (2011). Safety of Tirofiban in Acute Ischemic Stroke: The SaTIS trial. Stroke (in press)

Übersichtsarbeiten, Buchbeiträge, Handbuchbeiträge, Bücher

• Siebler M, Stoll G, Groth J (1992) Cogans syndrom presenting as psychosis in a geriatric patient. Geriat Forsch 2:227–230.
• Siebler M, Daffertshofer M, Nachtmann A, Link A, Worth H. (1994) Cerebrovaskuläre Dynamik während schlafbezogener Atemregulationsstörungen. In: Schlaf und autonome Störungen. Schläfke ME, Gehlen W, Schäfer (eds). Universitätsverlag Brockmeyer - Bochum. 333–337.
• Siebler M., Nachtmann A, Sitzer M, Steinmetz H, Freund H-J. (1994) Langzeitmonitoring während der Akutphase des ischämischen Hirninfarktes. In: Verhandlungen der Deutschen Gesellschaft für Neurologie. Jerusalem, Ries (eds). Köllen Druck und Verlag GmbH 386–388.
• Köller H, Siebler M. (1994)  Störung elektrischer Astrozytenfunktionen durch immunologische Aktivierung. In: Verhandlungen der Deutschen Gesellschaft für Neurologie. Jerusalem, Ries (eds). Köllen Druck und Verlag GmbH 486–488.
• Siebler M. Unser Gehirn – Neuronale Netzwerke. In: Sitzer G, Sitzer M (1995). Mensch und Gesundheit, Bertelsmann Lexikothek Verlag, Gütersloh, Germany,339–341.
• Siebler M. (1996) Neurologisches Monitoring auf der Stroke Unit. In: Fortbildungsakademie der Deutschen Neurologischen Gesellschaft. Diener, Felgenhauer, Wallesch (eds) F20-F26.
• Siebler M., Steinmetz H. (1997) Microembolidetection in patients with intracranial artery disease. In: New Trends in cerebral hemodynamics and neurosonology. Klingelhöfer, Bartels, Ringelstein (eds). Elsevier  412–415.
• Siebler M (1997) Mikroemboliedetektion: Theorie, Praxis und klinischer Stellenwert. Das EEG Labor 19: 20–37.
• Söhngen D, Siebler M., Wienen S, Kobbe G, Hollmig K, Schneider P, Boogen C, Heyll A, Schneider W. (1997) Untersuchungen der rhG-CSF-Wirkung auf Plättchen mittels In-vitro-Blutungszeit und transkranieller Doppleruntersuchung. In: Transfusionsmedizin. Sibrowski W, Stangel W, Müller N(eds), Karger:161–165.
• Siebler M, Sitzer M (1999) Ultraschalldiagnostik bei akutem Schlaganfall. ZaeFQ 93(3):175–181.
• Siebler M (2004) Akutbehandlung des Schlaganfalls. Notfall & Hausarztmedizin; 30:236–238.
• Siebler M, Laufen A. Können Decision Support Systeme in der akuten Schlaganfalltherapie helfen? Nervenheilkunde 2006;11:906–910.
• Thomalla G , Siebler M , Dohmen C, Dreier JP, Graf R, Röther J. Das Subnetz „Klinische Studien“ im Kompetenznetz Schlaganfall - Eine erfolgreiche Plattform für die Durchführung multizentrischer klinischer StudienThe „Clinical Trial Net“ within the German Competence Net Stroke - an effective platform for the realisation of clinical multicentre studies Nervenheilkunde 2006;11: 911–918.
• Siebler M. Klinische Ausbildung im Jahr 2010- Ärztemangel, Qualitätsverlußt und „Deprofessionalisierung“? Klinikarzt 2010;39:356–359.

Lehrbücher

• Hamann G, Siebler M, von Scheidt F (2002) Schlaganfall: Klinik, Diagnostik, Therapie: Interdisziplinäres Handbuch, Ecomed Verlag, 792 Seiten.
• Hamann G, Siebler M, Steiner G. (2004) Komplikationen nach akutem Schlaganfall, In Diener, Hacke Forsting. Schlaganfall Thieme Verlag.
• Siebler M. (2004) Das Nervensystem in Lupus Erythematodes (Hrsg Schneider) Steinkoff-Verlag.
• Siebler M: Arterielle Verschlusskrankheit der zerebralen Gefäße. In: C.Vallbracht, M.Kaltenbach (Hrsg). Herz-Kreislauf kompakt. Steinkopfverlag 2006.
• Lehrbuch der Neurologie (Steinmetz/Sitzer): Kapitel Neurorehabilitation /Thiemeverlag 2011.

Patente

• „Verfahren zum Hirnfunktionsmonitoring beim akuten Schlaganfall“. Deutsches Patent Nummer: 197 25 214, Internationales Patent für Europa und USA erteilt 1999.
• „Verfahren zum Neuroscreening mittels Neurochips“. Deutsches Patent Nummer: 199 32 720, erteilt 2003.

Diplomarbeiten

• M. Pekel (1991) Einfluß von Immunmediatoren auf elektrophysiologische Eigenschaften von kultivierten corticalen Neuronen der embryonalen Ratte. (Biologie, Note: gut)
• P. Vierke (1990) Entwicklung eines Multimodalen Monitors zur Erfassung von kardiovaskulären und zerebralen Messdaten bei Schlaganfallpatienten. (Medizinische Technik/FH-Aachen-Jülich, Note: gut)
• K. Walheim (1992) Entwicklung eines Kreislaufmodells zur Simulation und Messung von Mikroemboliesignalen. (Medizinische Technik/FH-Aachen-Jülich, Note: gut)
• K. Thiem (1995) Auswirkung der Stimulation durch Immunmediatoren auf elektrophysiologische Eigenschaften kultivierter Neuronen, Astrozyten und humaner Astrozytomzellen. (Biologie, Note: gut)
• F. Mölter (1995 )Elektrophysiologische Eigenschaften kleiner neuronaler Netzwerke: Messungen an kultivierten Zellen embryonaler Zellen des Rattenhirns. (Biologie, Note: gut)
• V. Schicks (1998)Entwicklung eines Atemmonitorgerätes für Schlaganfallpatienten. (Medizinische Technik/FH-Aachen-Jülich, Note: gut)
• T. Wiegand (2002) Entwicklung, Charakterisierung und Ableitung neuronaler Netzwerke auf Mikroelektrodenarrays. (Biologie, Note: sehr gut)

Promotionen

• A. Nachtmann (1995) Diagnostik und zerebrale Hämodynamik der obstruktiven Schlafapnoe. (Medizin; Note: magna cum laude)
• D. Bendfeldt (1999)  Cerebrale Mikroembolien bei Patienten mit stenosierenden Prozessen der Arteria carotis interna. (Medizin; Note: magna cum laude)
• U. Brauckmann (1999) Arterielle Mikroembolien nach perkutaner transluminaler Angioplastie. (Medizin, Note: cum laude)
• S. Mager (1999)  Intrinsische Aktivitätsmuster neuronaler Netzwerke. (Physik, Note: summa cum laude)
• J. Buchholz (2000) Verstärkung der Natriumstrom-Inaktivierung bei corticalen Neuronen durch Liquor von Patienten mit Multipler Sklerose. (Medizin: note: magna cum laude)
• P. Görtz (2001)  Enzephalopathie bei Ahornsirupkrankheit: Neurophysiologische Effekte von Leuzin und Ketoisocapronsäure. (Medizin, Note: magna cum laude)
• F. Hartmann (2002)  Transkranielle Dopplersonographie mit Mikroemboliedetektion beim Stenten der Arteria carotis interna. (Medizin, Note: cum laude)
• H. Astler (2002)  Automatisierte Identifikation mikroembolischer Signale: Vergleich der Arbitrary Sample Volume Methode mit der „Bigate“-Methode. (Medizin in Kooperation mit der Universität Halle-Wittenberg, Note: magna cum laude)
• V. Jovanovic (2004) Eine neue EEG-Methode zum Monitoring des akuten Schlaganfalls. (Note: magna cum laude)
• A. Hoinkes (2005)  Auswirkung von Homocystein und seinen Metaboliten auf die neuronale Netzwerkfunktion. (Medizin; Note: magna cum laude)
• W. Fleischer (2006) Biologie: Funktionelle Entwicklung striataler Netzwerke auf Mikroelektrodenarrays.
• A. Laufen (2007) Medizin: Evaluation des elektronischen Schlaganfallnavigators „Stroke Angel“ im Notfall.
• T. Brosig (2010) Medizin: Mikroembolien nach Carotisoperation.
• A. Schröter (2010) Medizin: Funktionelle Auswirkung von Metaboliten der Glutarsäure auf die Netzwerkfunktion.
• T. Schwarz (2010) Medizin: Diachisis beim akuten Schlaganfall? Befunde mit einem neuen EEG-Verfahren.
• J. Brune (2011) Medizin: Versorgungsrealität der Schlaganfallpatienten in der Postakutphase.

Habilitation

U. Junghans (2004)  Medizin: Pathogenetische Relevanz aktivierter Thrombozyten beim akuten Schlaganfall. (Medizin)

• 1994: Verleihung des Innovationspreises Nordrhein-Westfalen

• 2005: Ehrenauszeichnung der Stiftung Deutsche Schlaganfall-Hilfe durch Frau L.Mohn

• 2012: Verleihung des Medica Förderpreises für Interdisziplinäre Projekte

• 2020. Asklepios Award: Rehaboard

• 2022 Asklepios Award: Post Covid Reha